Yesterday we published a really nice Exchange Protocol entitled A highly-sensitive and rapid Surface Plasmon Resonance immunoassay procedure based on the covalent-orientated immobilization of antibodies. It is a variation on a recent Nature Protocol (Multisubstrate-compatible ELISA procedures for rapid and high-sensitivity immunoassays), where detection is via SPR rather than ELISA. And it is pleasing to me that we were able to accomodate both methods by using both Nature Protocols and the Protocol Exchange.
The Protocol Exchange is an open-access resource where scientists can share their protocols, and browse those that others have added. Exchange Protocols are accessed from a Browse page (which also includes entries from Nature Protocols), and can be either Community or Supplier Contributed.
My five favourite Exchange Protocols
Protocols on the Protocol Exchange are not peer-reviewed or edited, therefore the protocols highlighted are ones that are nice examples of using our format (i.e. ones that I happen to somehow please me!). If there are ones that you think should be included on this Top-Five list, then please let us know which are your favourites!
Exchange Protocols that have interesting comments
One of the really nice features of both Nature Protocols and the Protocol Exchange is that it is possible to comment on protocols. While this resource is under-utilised, there are a few protocols that have very interesting discussions associated with them, and I have highlighted these below.
A complete list of Exchange Protocols with comments can be found here.
Labgroups that have contributed loads of protocols.
It would be really great if research laboratories used the Protocol Exchange as a way to archive and share their methods within their group, with collaborators and with the wider community.
This has not really happened yet, but there are a few people who have uploaded collections of protocols either all relating to a single research paper or, in the case of Wei Zou, to a PhD thesis.
(a series of protocols relating to a Nature Structural and Molecular Biology paper)
Labgroups that have pretty logos
When you create a labgroup, you can add an image, or logo, to go with it. There are a few really pretty ones which I have listed below.