Self-coalescence occurs when a liquid is stretched and made to fold onto itself. Using microfluidics, their unique properties can be used to engineer and deliver precise sequences of reagents to realize complex portable bioassays.
Dynamic response of eukaryotes provide us with a signature of their response to stress, perturbations, sustained, cyclic, or periodic variations and fluctuations, and therefore the analysis of dynamic eukaryotic networks is elemental in achieving a mechanistic understanding of cellular behavior.
“Self-coalescence” of a liquid in a microstructure containing reagents can be programmed to master the dissolution profiles of picogram quantities of reagents in nanoliter volumes of solutions. This brings new options for chemistry and biosensing at the microscale.
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