Spatially resolved transcriptomics (SRTs) provide gene expression while retaining the locations of sequencing and providing matched pathology images; however, there are high levels of noise. We made Sprod to impute accurate SRT gene expression by leveraging their matched location and imaging data.

How can we quantify the nanoscale distribution of proteins on the cell surface? How can we tell if they are randomly distributed or not? The answer lies in a new data analysis method for single-molecule super-resolution microscopy.