Nature Communications
An open access, multidisciplinary journal dedicated to publishing high-quality research in all areas of the biological, health, physical, chemical and Earth sciences.
SnapFISH: a computational pipeline to identify chromatin loops from multiplexed DNA FISH data
Multiplexed DNA fluorescence in situ hybridization (FISH) imaging technology has been developed to map the folding of chromatin fibers at tens of nanometers and several kilobases in resolution in single cells. We present SnapFISH to process the multiplexed DNA FISH data and identify chromatin loops.