Multiplexed DNA fluorescence in situ hybridization (FISH) imaging technology has been developed to map the folding of chromatin fibers at tens of nanometers and several kilobases in resolution in single cells. We present SnapFISH to process the multiplexed DNA FISH data and identify chromatin loops.

Lindsay Lee and 2 others

Aug 14, 2023

Protocols and Methods Community

Nature Communications

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